| Date | Location | Result | |
| Dec 04, 2010 | Nacogdoches, TX | Villanova 54, Stephen F. Austin 24 | Box score |
| Nov 20, 2010 | Huntsville, TX | Sam Houston State 31, Texas State 29 | Box score |
| Nov 20, 2010 | Conway, AR | Central Arkansas 28, McNeese State 24 | Box score |
| Nov 20, 2010 | Nacogdoches, TX | Stephen F. Austin 36, Northwestern State 13 | Box score |
| Nov 18, 2010 | Thibodaux, LA | Nicholls 27, Southeastern La. 25 | Box score |
| Nov 13, 2010 | Lake Charles, LA | McNeese State 36, Texas State 6 | Box score |
| Nov 13, 2010 | Conway, AR | Sam Houston State 20, Central Arkansas 13 | Box score |
| Nov 13, 2010 | Nacogdoches, TX | Stephen F. Austin 51, Southeastern La. 14 | Box score |
| Nov 13, 2010 | Natchitoches, LA | Nicholls 37, Northwestern State 7 | Box score |
| Nov 06, 2010 | San Marcos, TX | Central Arkansas 49, Texas State 17 | Box score |
| Nov 06, 2010 | Hammond, LA | Northwestern State 35, Southeastern La. 16 | Box score |
| Nov 06, 2010 | Thibodaux, LA | Stephen F. Austin 48, Nicholls 13 | Box score |
| Nov 06, 2010 | Huntsville, TX | McNeese State 33, Sam Houston State 28 | Box score |
| Oct 30, 2010 | Conway, AR | Central Arkansas 30, Southeastern La. 23 | Box score |
| Oct 30, 2010 | Nacogdoches, TX | Texas State 27, Stephen F. Austin 24 | Box score |
| Oct 30, 2010 | Lake Charles, LA | McNeese State 24, Nicholls 14 | Box score |
| Oct 30, 2010 | Natchitoches, LA | Northwestern State 23, Sam Houston State 20 | Box score |
| Oct 23, 2010 | Hammond, LA | McNeese State 13, Southeastern La. 10 | Box score |
| Oct 23, 2010 | San Marcos, TX | Northwestern State 16, Texas State 3 | Box score |
| Oct 23, 2010 | Houston, TX | Stephen F. Austin 31, Sam Houston State 28 | Box score |
| Oct 23, 2010 | Thibodaux, LA | Central Arkansas 31, Nicholls 7 | Box score |
| Oct 16, 2010 | San Marcos, TX | Nicholls 47, Texas State 45 | Box score |
| Oct 16, 2010 | Baton Rouge, LA | LSU 32, McNeese State 10 | Box score |
| Oct 16, 2010 | Nacogdoches, TX | Stephen F. Austin 30, Central Arkansas 7 | Box score |
| Oct 16, 2010 | Huntsville, TX | Sam Houston State 57, Southeastern La. 7 | Box score |
| Oct 09, 2010 | Lake Charles, LA | Stephen F. Austin 32, McNeese State 27 | Box score |
| Oct 09, 2010 | Conway, AR | Northwestern State 24, Central Arkansas 19 | Box score |
| Oct 09, 2010 | Hammond, LA | Southeastern La. 49, Texas State 24 | Box score |
| Oct 09, 2010 | Thibodaux, LA | Sam Houston State 26, Nicholls 7 | Box score |
| Oct 02, 2010 | Beaumont, TX | Sam Houston State 38, Lamar 10 | Box score |
| Oct 02, 2010 | Natchitoches, LA | McNeese State 24, Northwestern State 7 | Box score |
| Sep 25, 2010 | Tulsa, OK | Tulsa 41, Central Arkansas 14 | Box score |
| Sep 25, 2010 | San Marcos, TX | Texas State 42, Southern Utah 28 | Box score |
| Sep 25, 2010 | Monroe, LA | Louisiana-Monroe 21, Southeastern La. 20 | Box score |
| Sep 25, 2010 | Thibodaux, LA | Nicholls 44, Bacone College 28 | Box score |
| Sep 25, 2010 | Lake Charles, LA | Cal Poly 40, McNeese State 14 | Box score |
| Sep 25, 2010 | Nacogdoches, TX | Stephen F. Austin 71, Lamar 3 | Box score |
| Sep 25, 2010 | Huntsville, TX | Sam Houston State 30, Gardner-Webb 14 | Box score |
| Sep 25, 2010 | Grand Forks, ND | North Dakota 49, Northwestern State 24 | Box score |
| Sep 18, 2010 | Mobile, AL | South Alabama 39, Nicholls 21 | Box score |
| Sep 18, 2010 | Cedar Falls, IA | Stephen F. Austin 22, Northern Iowa 20 | Box score |
| Sep 18, 2010 | Conway, AR | Central Arkansas 21, Murray State 20 | Box score |
| Sep 18, 2010 | San Marcos, TX | Texas State 21, Cal Poly 12 | Box score |
| Sep 18, 2010 | Hammond, LA | Lamar 29, Southeastern La. 28 | Box score |
| Sep 18, 2010 | Natchitoches, LA | Northwestern State 17, Tarleton 14 | Box score |
| Sep 18, 2010 | Macomb, IL | Western Illinois 56, Sam Houston State 14 | Box score |
| Sep 11, 2010 | Charleston, IL | Central Arkansas 37, Eastern Illinois 7 | Box score |
| Sep 11, 2010 | Nacogdoches, TX | Stephen F. Austin 59, Albany 14 | Box score |
| Sep 11, 2010 | San Marcos, TX | Texas State 31, Southern Arkansas 17 | Box score |
| Sep 11, 2010 | Hammond, LA | Southeastern La. 24, UT Martin 10 | Box score |
| Sep 11, 2010 | Columbia, MO | Missouri 50, McNeese State 6 | Box score |
| Sep 11, 2010 | Kalamazoo, MI | Western Michigan 49, Nicholls 14 | Box score |
| Sep 11, 2010 | Natchitoches, LA | Samford 19, Northwestern State 7 | Box score |
| Sep 04, 2010 | Houston, TX | Houston 68, Texas State 28 | Box score |
| Sep 04, 2010 | College Station, TX | Texas A&M 48, Stephen F. Austin 7 | Box score |
| Sep 04, 2010 | USAFA, CO | Air Force 65, Northwestern State 21 | Box score |
| Sep 04, 2010 | San Diego, CA | San Diego State 47, Nicholls 0 | Box score |
| Sep 04, 2010 | Lake Charles, LA | McNeese State 30, Lamar 27 | Box score |
| Sep 04, 2010 | Waco, TX | Baylor 34, Sam Houston State 3 | Box score |
| Sep 02, 2010 | Conway, AR | Central Arkansas 47, Elizabeth City State 20 | Box score |
| Sep 02, 2010 | New Orleans, LA | Tulane 27, Southeastern La. 21 | Box score |